Biologia, Bratislava, 56/Suppl. 9: 81-85, 2001.

ISSN 0006-3088 (Biologia). ISSN 1335-6399 (Biologia. Section Cellular and Molecular Biology).


Full Paper

The possibilities of influencing the transmission of VHB in health service establishments.


Maria Stefkovicova*, Miloslava Rumlerova & Kvetoslava Orlovska

State Institute of Health, Hospital Trencin, Nemocnicna 4, SK-91101 Trencin, Slovakia; fax: ++ 421 831 6521232, e-mail:

* corresponding author

Received: December 28, 2000 / Accepted: April 23, 2001



Authors have been analysing five cases of nosocomial hepatitis B. Three cases proceeded as fulminating form. Serological markers of VHB were consistently the same in all patients; HBeAg negative and other positive markers have confirmed diagnosis of acute hepatitis B. Health service establishments are places with an increased occurrence HBsAg carriers in comparison with the general population. There is an accumulation of parenteral and non-parenteral transmission of infection. Skin defects and bleeding sites of HBsAg positive patients represent important factors of the contamination of the environment. In addition, skin defects represent an important site of entry into HBsAg negative patients. It is possible to reduce a nosocomial occurrence of VHB by combination of a strict hygiene-epidemiological regimes and vaccination of high-risk patients.


Key words: viral hepatitis B, nosocomial infection, prevention of transmission, HBs-antigen carriers.