Biologia, Bratislava, 56/Suppl. 9: 21-25, 2001.
ISSN 0006-3088 (Biologia). ISSN 1335-6399 (Biologia. Section Cellular and Molecular Biology).
Andrea Longauerova*, Daniela Kotulova1, Livia Slobodnikova1, Juraj Horvath2 & Lubica Klokocnikova1
1 Institute of Microbiology, Faculty of Medicine and Faculty Hospital, Comenius University, Sasinkova 4, SK-81108 Bratislava, Slovakia; tel.: ++ 421 2 59357207, fax: ++ 421 2 59357583, e-mail: email@example.com
2 1st Department of Orthopaedics, Faculty of Medicine and Faculty Hospital, Comenius University, Hlboka 7, SK-81105 Bratislava, Slovakia
* corresponding author
Received: December 18, 2000 / Accepted: July 6, 2001
In the period from July 1995 to December 1999 total hip joint replacements were performed in 1219 patients of the 1st Department of Orthopaedics of the Faculty of Medicine and Faculty Hospital. Three types of total hip prostheses were implanted: cemented, cementless and hybrid. Samples from 118 patients with signs of inflammation in the implanted area were collected and examined for the presence of aerobic and anaerobic bacteria. Quantitative antibiotic susceptibility of isolated and identified strains was tested. Samples of 71 patients yielded positive culture results (5.8% of total number of patients with implants). Coagulase-negative staphylococci, Pseudomonas aeruginosa and other gram-negative non-fermenting bacteria were the most frequent bacterial agents infecting the prosthetic hips of patients in the study. Cemented hip prostheses were the most frequently infected type. The infection of 29 patients in the study was cured by intensive therapy (antimicrobial resp. surgical and/or immunotherapy). Hip prostheses of 67% patients with therapeutical failure were infected with Pseudomonas aeruginosa and other gram-negative non fermenting bacteria.
Key words: hip prostheses, coagulase negative staphylococci, Pseudomonas aeruginosa, gram negative non fermenting bacteria.